GlaxoSmithKline Plc: On Track To Deliver 2024 Outlooks With Further Good Progress Made In R&D

GSK: Q3 2024 sales and core earnings growth driven by the strong performance of Specialty Medicines helping to offset lower Vaccines sales:
  • Total Q3 2024 sales £8.0 billion -2% AER; +2% CE
  • Vaccines sales -15%. Shingrix -7% and Arexvy -72% reflecting ACIP guideline changes, prioritisation of COVID vaccinations in the US and annualisation of Arexvy launch in Q3 2023
  • Specialty Medicines sales +19%. HIV sales +12%. Oncology +94%. Respiratory/Immunology and other +14%
  • General Medicines sales +7%. Trelegy +16%
  • Total operating profit -86% and Total EPS -100% driven by a charge of £1.8 billion ($2.3 billion) in relation to the Zantac settlement
  • Core operating profit +5% and Core EPS +5% reflecting strong Specialty Medicines performance, together with effective cost management
  • Cash generated from operations in the quarter was £2.5 billion with Free cash flow of £1.3 billion
  Q3 2024 Year to date
  £m % AER % CER £m % AER % CER
Turnover 8,012 (2) 2 23,259 4 8
Turnover ex COVID 8,012 (2) 2 23,258 5 9
Total operating profit 189 (90) (86) 3,325 (46) (41)
Total operating margin % 2.4% (21.6ppts) (20.6ppts) 14.3% (13.4ppts) (12.5ppts)
Total EPS (1.4p) >(100) (100) 53.0p (53) (48)
Core operating profit 2,761 5 7,717 10 16
Core operating margin % 34.5% 0.4ppts 1.0ppts 33.2% 1.6ppts 2.2ppts
Core EPS 49.7p (1) 5 136.2p 8 14
Cash generated from operations 2,499   5,275 19
Further progress in R&D with growth prospects strengthened in all key therapeutic areas:
  • Infectious Diseases: EU approval for Arexvy in adults aged 50-59 at increased risk, and positive new data indicates protection over three RSV seasons; US FDA file acceptance for gepotidacin in uncomplicated UTI; bepirovirsen granted SENKU designation in Japan for chronic hepatitis B
  • HIV: Real-world studies demonstrate 99% effectiveness for Apretude, the only approved long-acting medicine for HIV PrEP
  • Respiratory/Immunology: Positive results announced for ultra long-acting biologic, depemokimab, for phase III ANCHOR trial (CRSwNP)(1) and full results for SWIFT-1&2 trials (severe asthma) supporting filing for severe asthma and CRSwNP before year end with dual indication, potential launch in 2025. Positive headline results announced for phase III MATINEE trial for Nucala in COPD. Nucala approved in Japan for CRSwNP
  • Oncology: Expanded US FDA approval for Jemperli in endometrial cancer; Blenrep filed in the US, EU and Japan and received Breakthrough Therapy Designation in China; US FDA Breakthrough Therapy Designation for GSK5764227 (B7-H3-targeted antibody-drug conjugate) in small-cell lung cancer
2024 guidance confirmed; Q3 2024 dividend of 15p declared and continue to expect 60p full year dividend:
  • 2024 turnover growth of 7% to 9%; Core operating profit growth of 11% to 13%; Core EPS growth of 10% to 12%. Expected to deliver broadly around the middle of existing ranges
Emma Walmsley, Chief Executive Officer, GSK:
“We have delivered another quarter of sales and core operating profit growth, and further good progress in R&D. Strong growth in speciality medicines helped to offset lower vaccine sales and reflected successful new product launches in oncology and HIV, as well as the resilience we have now built into GSK’s portfolio and performance. Our pipeline continues to strengthen with 11 positive phase III trials reported so far this year and we are currently planning launches for 5 major new product approval opportunities next year: Blenrep, Depemokimab, Nucala for COPD, Gepotidacin, and our new vaccine to prevent meningitis (MenABCWY). We also resolved the vast majority of Zantac litigation in the quarter, to remove uncertainty and so we can focus forward. All this means we are on track to deliver our 2024 guidance, and we are even more confident in our 2026 and 2031 outlooks.”
For the full document click the link below:
GlaxoSmithKline Plc
Stay ahead of the curve! Subscribe to InsidEntity for daily updates on all your favourite companies.